Protein Purification Scientist

Our large pharmaceutical client in Spring House, PA is seeking a lab-based Protein Purification Scientist to work in a fast-paced R&D environment applying rigorous scientific principles towards groundbreaking biological therapeutics. This person will employ protein purification and biochemistry techniques to assist in discovering new medicines. In this capacity, they will purify and characterize monoclonal antibodies, multispecifics, and other biomolecules to enable robust in vitro characterization and in vivo studies, and will use AKTA systems to purify proteins via affinity and other chromatography methods such as size exclusion and ion exchange. They will also use HPLCs and other biochemical analytical techniques for characterization. Primary responsibilities include:

-Make the highest quality lead candidate proteins using protein purification platforms such as AKTA FPLC
-Take requests from the Protein Expression team and change from unpurified raw material to fully purified material in ~2-week turnaround by employing chromatography techniques such as affinity, ion exchange and size exclusion to ultimately release the protein to the user who needs it for their study
-Design, execute, and interpret experiments
-Maintain accurate laboratory notebooks in a timely fashion and prepare technical reports, summaries, protocols, etc.
-Collaborate and communicate with other scientists in a multifaceted and dynamic research environment

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to HR@insightglobal.com.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: https://insightglobal.com/workforce-privacy-policy/.

-A minimum of a bachelor's degree in Biochemistry or related field
-2+ years of protein purification experience in industry (ideally 3-5 years) with FPLC (Fast Protein Liquid Chromatography) techniques size exclusion, affinity, and ion exchange
-Experience with AKTA systems
-Experience with protein purification and characterization combined with an understanding of therapeutic proteins and the drug discovery process

-Experience with bispecific or multi-specific antibodies, novel protein therapeutics, and antibody mechanisms of action
-Mammalian cell culture experience
-Molecular biology knowledge (cloning, PCR)

Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.